Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100500 | 1.00 | HTR2A (0.51) | HTR2ASKP2ESR1ADRA2AADORA3 | |
| SCHEMBL8094156 | 1.00 | HTR2A (0.51) | HTR2ASKP2ESR1ADRA2AADORA3 | |
| SCHEMBL8098050 | 1.00 | HTR2A (0.51) | HTR2ASKP2ESR1ADRA2AADORA3 | |
| SCHEMBL8101948 | 1.00 | HTR2A (0.51) | HTR2ASKP2ESR1ADRA2AADORA3 | |
| SCHEMBL8096647 | 1.00 | HTR2A (0.51) | HTR2ASKP2ESR1ADRA2AADORA3 | |
| SCHEMBL8101711 | 1.00 | HTR2A (0.51) | HTR2ASKP2ESR1ADRA2AADORA3 | |
| SCHEMBL8093788 | 1.00 | HTR2A (0.51) | HTR2ASKP2ESR1ADRA2AADORA3 | |
| SCHEMBL8101341 | 1.00 | HTR2A (0.51) | HTR2ASKP2ESR1ADRA2AADORA3 | |
| SCHEMBL8094486 | 1.00 | HTR2A (0.51) | HTR2ASKP2ESR1ADRA2AADORA3 | |
| SCHEMBL8086520 | 1.00 | HTR2A (0.51) | HTR2ASKP2ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |