Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087030 | 1.00 | CYP19A1 (0.39) | CYP19A1GRM2ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL8094541 | 1.00 | CYP19A1 (0.39) | CYP19A1GRM2ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL8086328 | 1.00 | CYP19A1 (0.39) | CYP19A1GRM2ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL8085975 | 1.00 | CYP19A1 (0.39) | CYP19A1GRM2ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL8099768 | 1.00 | CYP19A1 (0.39) | CYP19A1GRM2ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL8095609 | 1.00 | CYP19A1 (0.39) | CYP19A1GRM2ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL8087419 | 1.00 | CYP19A1 (0.39) | CYP19A1GRM2ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL8099769 | 1.00 | CYP19A1 (0.39) | CYP19A1GRM2ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL8860519 | 1.00 | CYP19A1 (0.39) | CYP19A1GRM2ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL8093912 | 1.00 | CYP19A1 (0.39) | CYP19A1GRM2ALDH1A1L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |