Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18363110 | 0.91 | CYP4F2 (0.55) | CYP4F2CYP4A11ALDH1A1CYP2D6HCAR2 | |
| SCHEMBL12788167 | 0.83 | CYP4F2 (0.48) | CYP4F2CYP4A11ALDH1A1CYP2D6PKM | |
| SCHEMBL14873553 | 0.82 | CYP4F2 (0.52) | CYP4F2CYP4A11ALDH1A1PKMMMP8 | |
| SCHEMBL14231593 | 0.81 | CYP4F2 (0.47) | CYP4F2CYP4A11ALDH1A1CYP2D6HCAR2 | |
| SCHEMBL19867008 | 0.81 | CYP4F2 (0.47) | CYP4F2CYP4A11ALDH1A1CYP2D6HCAR2 | |
| SCHEMBL16866690 | 0.79 | CYP4F2 (0.55) | CYP4F2CYP4A11ALDH1A1CYP2D6PKM | |
| SCHEMBL761783 | 0.78 | CYP4F2 (0.48) | CYP4F2CYP4A11ALDH1A1PKMMMP8 | |
| SCHEMBL12370572 | 0.78 | CYP4F2 (0.48) | CYP4F2CYP4A11ALDH1A1PKMMMP8 | |
| SCHEMBL8209270 | 0.78 | CYP4F2 (0.48) | CYP4F2CYP4A11ALDH1A1PKMMMP8 | |
| SCHEMBL10027503 | 0.78 | CYP4F2 (0.48) | CYP4F2CYP4A11ALDH1A1PKMMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847809-B1 | OLIGOMERIC ORGANIC LIGHT EMITTING DIODE(OLED)MATERIALS CONTAINING MULTIPLE CROSSLINKING FUNCTIONS | LOMOX LTD (GB) | 2017-12-20 | — | — | EP | disclosed |
| WO-2009036066-A1 | VEGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |