Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 6/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.57 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.57 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.57 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.57 |
| ▸ | EP300 | Q09472 | 2/20 | 0.57 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.57 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.57 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.57 |
| ▸ | F7 | P08709 | 3/20 | 0.50 |
| ▸ | F3 | P13726 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100825 | 1.00 | BID (0.57) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL8098414 | 1.00 | BID (0.57) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL8094459 | 0.98 | BID (0.55) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL8094015 | 0.94 | BID (0.49) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL7420497 | 0.87 | ITGB1 (0.43) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL16250350 | 0.86 | BID (0.72) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL8096083 | 0.84 | BID (0.57) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL8100395 | 0.84 | BID (0.57) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL8096206 | 0.84 | BID (0.57) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL9342117 | 0.84 | BID (0.69) | BIDMCL1BCL2L1BAK1KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |