Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.68 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PPARD | Q03181 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL21409815 | 0.98 | EPHX1 (0.71) | EPHX1S1PR2S1PR4S1PR1S1PR3 | |
| Acetic Acid SCHEMBL28429473 | 0.98 | EPHX1 (0.71) | EPHX1S1PR2S1PR4S1PR1S1PR3 | |
| Acetic Acid SCHEMBL10610697 | 0.98 | EPHX1 (0.71) | EPHX1S1PR2S1PR4S1PR1S1PR3 | |
| Acetic Acid SCHEMBL5575013 | 0.98 | EPHX1 (0.71) | EPHX1S1PR2S1PR4S1PR1S1PR3 | |
| Acetic Acid SCHEMBL11575382 | 0.98 | EPHX1 (0.71) | EPHX1S1PR2S1PR4S1PR1S1PR3 | |
| Acetic Acid SCHEMBL5568053 | 0.98 | EPHX1 (0.71) | EPHX1S1PR2S1PR4S1PR1S1PR3 | |
| Bicarbonate SCHEMBL28549811 | 0.91 | EPHX1 (0.75) | EPHX1S1PR2S1PR4S1PR1S1PR3 | |
| Bicarbonate SCHEMBL28549810 | 0.91 | EPHX1 (0.75) | EPHX1S1PR2S1PR4S1PR1S1PR3 | |
| Bicarbonate SCHEMBL28237747 | 0.91 | EPHX1 (0.75) | EPHX1S1PR2S1PR4S1PR1S1PR3 | |
| Bicarbonate SCHEMBL5430860 | 0.91 | EPHX1 (0.75) | EPHX1S1PR2S1PR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6106906-A | FORMING ELECTROCONDUCTIVE FILM OF ORGANOMETALLIC COMPLEX | CANON KABUSHIKI KAISHA (JP) | 2000-08-22 | — | — | US | disclosed |