Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093810 | 1.00 | TAAR1 (0.65) | TAAR1HRH3IDO1ACHENAAA | |
| SCHEMBL8101532 | 1.00 | TAAR1 (0.65) | TAAR1HRH3IDO1ACHENAAA | |
| SCHEMBL8101372 | 1.00 | TAAR1 (0.65) | TAAR1HRH3IDO1ACHENAAA | |
| SCHEMBL8086943 | 1.00 | TAAR1 (0.65) | TAAR1HRH3IDO1ACHENAAA | |
| SCHEMBL8092438 | 1.00 | TAAR1 (0.65) | TAAR1HRH3IDO1ACHENAAA | |
| SCHEMBL8095693 | 1.00 | TAAR1 (0.65) | TAAR1HRH3IDO1ACHENAAA | |
| SCHEMBL8102622 | 1.00 | TAAR1 (0.65) | TAAR1HRH3IDO1ACHENAAA | |
| SCHEMBL8094389 | 1.00 | TAAR1 (0.65) | TAAR1HRH3IDO1ACHENAAA | |
| SCHEMBL8093918 | 1.00 | TAAR1 (0.65) | TAAR1HRH3IDO1ACHENAAA | |
| SCHEMBL8100077 | 1.00 | TAAR1 (0.65) | TAAR1HRH3IDO1ACHENAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |