Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 1/20 | 0.40 |
| ▸ | ATP4B | P51164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096077 | 0.97 | SKP2 (0.53) | SKP2CA2SMN1; SMN2HTR2AATP4A | |
| SCHEMBL8093757 | 0.95 | SKP2 (0.51) | SKP2CA2SMN1; SMN2HTR2AALDH1A1 | |
| SCHEMBL8093713 | 0.95 | SKP2 (0.51) | SKP2CA2SMN1; SMN2HTR2AALDH1A1 | |
| SCHEMBL8095213 | 0.95 | SKP2 (0.51) | SKP2CA2SMN1; SMN2HTR2AALDH1A1 | |
| SCHEMBL8099884 | 0.95 | SKP2 (0.51) | SKP2CA2SMN1; SMN2HTR2AALDH1A1 | |
| SCHEMBL8102308 | 0.95 | SKP2 (0.51) | SKP2CA2SMN1; SMN2HTR2AALDH1A1 | |
| SCHEMBL8099719 | 0.95 | SKP2 (0.51) | SKP2CA2SMN1; SMN2HTR2AALDH1A1 | |
| SCHEMBL8096212 | 0.95 | SKP2 (0.51) | SKP2CA2SMN1; SMN2HTR2AALDH1A1 | |
| SCHEMBL8092708 | 0.95 | SKP2 (0.51) | SKP2CA2SMN1; SMN2HTR2AALDH1A1 | |
| SCHEMBL8096642 | 0.95 | SKP2 (0.51) | SKP2CA2SMN1; SMN2HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |