Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1186424 | 0.97 | GSK3B (0.81) | GSK3B | |
| SCHEMBL8101471 | 0.95 | GSK3B (0.80) | GSK3B | |
| SCHEMBL8095135 | 0.94 | GSK3B (0.67) | GSK3B | |
| SCHEMBL1186600 | 0.94 | GSK3B (0.69) | GSK3B | |
| SCHEMBL12874188 | 0.92 | GSK3B (0.72) | GSK3B | |
| SCHEMBL12874295 | 0.91 | GSK3B (0.72) | GSK3B | |
| SCHEMBL12874191 | 0.91 | GSK3B (0.81) | GSK3B | |
| SCHEMBL12874424 | 0.89 | GSK3B (0.59) | GSK3B | |
| SCHEMBL8093162 | 0.88 | GSK3B (0.61) | GSK3B | |
| SCHEMBL12874337 | 0.88 | GSK3B (0.61) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476261-B2 | Spirocyclic aminoquinolones as GSK-3 inhibitors | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2013-07-02 | — | — | US | disclosed |
| WO-2009035684-A1 | SPIROCYCLIC AMINOQUINOLONES AS GSK-3 INHIBITORS | ACTIVX BIOSCIENCES, INC. (US) | 2009-03-19 | — | — | WO | disclosed |