Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094827 | 1.00 | IDO1 (0.46) | IDO1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8094839 | 1.00 | IDO1 (0.46) | IDO1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9061568 | 0.95 | IDO1 (0.48) | IDO1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9061563 | 0.95 | IDO1 (0.48) | IDO1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9060835 | 0.91 | IDO1 (0.46) | IDO1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9060840 | 0.91 | IDO1 (0.46) | IDO1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9060950 | 0.89 | IDO1 (0.44) | IDO1MEN1KMT2ALMNAHTT | |
| SCHEMBL7513854 | 0.89 | CYP2C9 (0.48) | IDO1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL10337587 | 0.89 | CYP2C9 (0.48) | IDO1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9060940 | 0.89 | IDO1 (0.44) | IDO1MEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166798-A | TN cell having improved display of grey shades | MERCK KGAA (DE) | 2000-12-26 | — | — | US | disclosed |
| EP-0592635-B1 | TN CELL WITH IMPROVED GREY-SHADE REPRESENTATION | MERCK PATENT GMBH (DE) | 1998-10-14 | — | — | EP | disclosed |