Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27862369 | 0.86 | TSHR (0.72) | TSHRMEN1KMT2AMAPTRAB9A | |
| SCHEMBL28050912 | 0.85 | TSHR (0.77) | TSHRMEN1KMT2AMAPTRAB9A | |
| SCHEMBL1026131 | 0.84 | TSHR (0.74) | TSHRMEN1KMT2AMAPTRAB9A | |
| SCHEMBL264768 | 0.84 | TSHR (1.00) | TSHRMEN1KMT2AMAPTRAB9A | |
| SCHEMBL2767396 | 0.82 | TSHR (0.72) | TSHRMEN1KMT2AMAPTRAB9A | |
| SCHEMBL27865552 | 0.82 | TSHR (0.72) | TSHRMEN1KMT2AMAPTRAB9A | |
| SCHEMBL27455525 | 0.82 | TSHR (0.96) | TSHRMEN1KMT2AMAPTRAB9A | |
| SCHEMBL844701 | 0.82 | TSHR (0.72) | TSHRMEN1KMT2AMAPTRAB9A | |
| Hydrochloric Acid SCHEMBL11553659 | 0.82 | TSHR (0.96) | TSHRMEN1KMT2AMAPTRAB9A | |
| SCHEMBL16955993 | 0.81 | TSHR (0.71) | TSHRMEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |