Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 9/20 | 0.45 |
| ▸ | MMP1 | P03956 | 4/20 | 0.45 |
| ▸ | MMP3 | P08254 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094019 | 1.00 | CSNK1E (0.60) | CSNK1ECNR2DNM1MMP2MMP1 | |
| SCHEMBL8094075 | 1.00 | CSNK1E (0.60) | CSNK1ECNR2DNM1MMP2MMP1 | |
| SCHEMBL8094331 | 1.00 | CSNK1E (0.60) | CSNK1ECNR2DNM1MMP2MMP1 | |
| SCHEMBL8093624 | 1.00 | CSNK1E (0.60) | CSNK1ECNR2DNM1MMP2MMP1 | |
| SCHEMBL8100368 | 1.00 | CSNK1E (0.60) | CSNK1ECNR2DNM1MMP2MMP1 | |
| SCHEMBL8093074 | 1.00 | CSNK1E (0.60) | CSNK1ECNR2DNM1MMP2MMP1 | |
| SCHEMBL8093653 | 0.98 | CSNK1E (0.57) | CSNK1ECNR2DNM1MMP2MMP1 | |
| SCHEMBL30903825 | 0.96 | CSNK1E (0.60) | CSNK1ECNR2DNM1MMP2MMP1 | |
| SCHEMBL29199074 | 0.96 | CSNK1E (0.60) | CSNK1ECNR2DNM1MMP2MMP1 | |
| SCHEMBL22806767 | 0.96 | CSNK1E (0.60) | CSNK1ECNR2DNM1MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |