Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095326 | 1.00 | CHRM2 (0.32) | CHRM2CHRM5CHRM1CHRM3TLR4 | |
| SCHEMBL8906439 | 1.00 | CHRM2 (0.32) | CHRM2CHRM5CHRM1CHRM3TLR4 | |
| SCHEMBL8747891 | 0.94 | CHRM2 (0.32) | CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL6451206 | 0.94 | TLR4 (0.32) | CHRM2CHRM5CHRM1CHRM3TLR4 | |
| SCHEMBL6451204 | 0.94 | TLR4 (0.32) | CHRM2CHRM5CHRM1CHRM3TLR4 | |
| SCHEMBL5683928 | 0.90 | — | — | |
| SCHEMBL5683925 | 0.90 | — | — | |
| SCHEMBL8450678 | 0.88 | — | — | |
| SCHEMBL8747992 | 0.86 | CYP1A2 (0.34) | CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL8451961 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628532-B1 | Fluorobenzole derivatives and mesomorphous medium | MERCK PATENT GMBH (DE) | 2000-01-19 | — | — | EP | disclosed |
| US-5641429-A | STABLE COMPOUNDS HAVING LOW VISCOSITY AND HIGH DIELECTRIC ANISOTROPY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-06-24 | — | — | US | disclosed |
| US-5536442-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5487845-A | ELECTROOPTICAL DISPLAY ELEMENTS; CHEMICAL, HEAT AND LIGHT STABILITY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-01-30 | — | — | US | disclosed |
| EP-0441932-B1 | FLUOROBENZOLE DERIVATIVES AND MESOMORPHOUS MEDIUM | MERCK PATENT GMBH (DE) | 1995-03-15 | — | — | EP | disclosed |
| EP-0628532-A1 | Fluorobenzole derivatives and mesomorphous medium | MERCK PATENT GmbH (DE) | 1994-12-14 | — | — | EP | disclosed |
| WO-1991003450-A1 | FLUOROBENZOLE DERIVATIVES AND MESOMORPHOUS MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-03-21 | — | — | WO | disclosed |