Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784240 | 0.79 | FOLH1 (0.45) | FFAR4FFAR1AKR1B1KMT2AMAPT | |
| SCHEMBL11749293 | 0.78 | FFAR4 (0.69) | FFAR4FFAR1AKR1B1KMT2AMAPT | |
| SCHEMBL12384963 | 0.78 | FFAR4 (0.69) | FFAR4FFAR1AKR1B1KMT2AMAPT | |
| SCHEMBL29962629 | 0.78 | FFAR4 (0.69) | FFAR4FFAR1AKR1B1KMT2AMAPT | |
| SCHEMBL10942819 | 0.78 | FFAR4 (0.69) | FFAR4FFAR1AKR1B1KMT2AMAPT | |
| SCHEMBL12506523 | 0.78 | FFAR4 (0.69) | FFAR4FFAR1AKR1B1KMT2AMAPT | |
| SCHEMBL2349520 | 0.78 | FFAR4 (0.69) | FFAR4FFAR1AKR1B1KMT2AMAPT | |
| SCHEMBL21772258 | 0.78 | FFAR4 (0.69) | FFAR4FFAR1AKR1B1KMT2AMAPT | |
| SCHEMBL3249933 | 0.78 | AKR1B1 (0.56) | FFAR4FFAR1AKR1B1KMT2AMAPT | |
| SCHEMBL3253370 | 0.78 | AKR1B1 (0.56) | FFAR4FFAR1AKR1B1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117902-A | 6,8-dimercaptooctanoic acid derivatives substituted at the 6-S and/or 8-S position with the (3-methylthiopropanoyl) radical and pharmaceutical compositions intended for the treatment of cancerous tumors | GALDERMAN RESEARCH & DEVELOPMENT, S.N.C. SOPHIA ABTIPOLIS (FR) | 2000-09-12 | — | — | US | disclosed |