Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096595 | 1.00 | HTR2A (0.43) | HTR2AMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL8094667 | 1.00 | HTR2A (0.43) | HTR2AMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL8095444 | 1.00 | HTR2A (0.43) | HTR2AMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL8096015 | 1.00 | HTR2A (0.43) | HTR2AMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL8094080 | 1.00 | HTR2A (0.43) | HTR2AMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL8094168 | 1.00 | HTR2A (0.43) | HTR2AMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL8087120 | 1.00 | HTR2A (0.43) | HTR2AMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL8094045 | 1.00 | HTR2A (0.43) | HTR2AMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL8085641 | 1.00 | HTR2A (0.43) | HTR2AMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL8101766 | 1.00 | HTR2A (0.43) | HTR2AMAOBALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |