Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.45 |
| ▸ | FNTA | P49354 | 16/20 | 0.43 |
| ▸ | FNTB | P49356 | 16/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 13/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446560 | 0.92 | FNTA (0.45) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8097931 | 0.91 | KMT2A (0.51) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8098288 | 0.89 | FNTA (0.43) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8095468 | 0.89 | FNTA (0.43) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8088439 | 0.88 | FNTA (0.52) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8101380 | 0.88 | FNTA (0.43) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8104352 | 0.88 | FNTA (0.43) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8097380 | 0.87 | FNTA (0.48) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8101584 | 0.87 | FNTA (0.43) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8097850 | 0.87 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |