SCHEMBL809633

SCHEMBL809633

C=CC(=O)NCC=CC.C=CCNC(=O)C=C

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
ALDH1A1 P00352 3/20 0.46
MAPK1 P28482 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
MAPT P10636 1/20 0.45
FAAH O00519 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
KMT2A Q03164 2/20 0.38
RAB9A P51151 2/20 0.37
NPC1 O15118 1/20 0.37
NPSR1 Q6W5P4 1/20 0.35
PKM P14618 1/20 0.34
MEN1 O00255 1/20 0.33
TGM2 P21980 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125985 0.94
SCHEMBL30851 0.85
Dimethylamine SCHEMBL3821887 0.83 TSHR (0.54) TSHRALDH1A1MAPK1TDP1SMN1; SMN2
Charcoal, Activated SCHEMBL890031 0.83
Methane SCHEMBL27388128 0.83
Ammonia Solution, Strong SCHEMBL1076016 0.83
Trimethylammonium SCHEMBL28033781 0.81 TSHR (0.52) TSHRALDH1A1MAPK1TDP1SMN1; SMN2
SCHEMBL11874311 0.81 TSHR (0.56) TSHRALDH1A1MAPK1TDP1SMN1; SMN2
SCHEMBL17732989 0.80 TSHR (0.46) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL19291830 0.78 TSHR (0.45) TSHRALDH1A1MAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090071618-A1 HIGH-PERFORMANCE STRENGTH RESINS IN PAPERMAKING INDUSTRIES KEMIRA OYJ (FI) 2009-03-19 US claimed
EP-1828479-A1 HIGH-PERFORMANCE STRENGTH RESINS IN PAPERMAKING INDUSTRIES Lanxess Corporation (US) 2007-09-05 EP claimed
WO-2006016906-A1 HIGH-PERFORMANCE STRENGTH RESINS IN PAPERMAKING INDUSTRIES LANXESS CORPORATION (US) 2006-02-16 WO claimed
EP-3571348-B1 HIGH MOLECULAR WEIGHT TEMPORARY WET STRENGTH RESIN FOR PAPER SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2024-03-06 EP disclosed
US-11028538-B2 Composition and method for increasing wet and dry paper strength SOLENIS TECHNOLOGIES, L.P. (US) 2021-06-08 US disclosed
US-10954633-B2 Process for making paper, paperboard or the like KEMIRA OYJ (FI) 2021-03-23 US disclosed
US-20200277735-A1 COMPOSITION AND METHOD FOR INCREASING WET AND DRY PAPER STRENGTH SOLENIS TECHNOLOGIES, L.P. (US) 2020-09-03 US disclosed
EP-3481994-B1 PROCESS FOR MAKING PAPER, PAPERBOARD OR THE LIKE KEMIRA OYJ (FI) 2020-04-15 EP disclosed
US-20180327974-A1 Process for making paper, paperboard or the like KEMIRA OYJ (FI) 2018-11-15 US disclosed
EP-3044365-B1 HIGH MOLECULAR WEIGHT AND HIGH CATIONIC CHARGEGLYOXALATEDPOLYACRYLAMIDE COPOLYMERS, AND THEIR METHODS OF MANUFACTURE AND USE BASF SE (DE) 2018-05-23 EP disclosed
EP-2788392-B1 PREPARATION OF POLYVINYLAMIDE CELLULOSE REACTIVE ADDUCTS BASF SE (DE) 2018-02-21 EP disclosed
US-20110083821-A1 GLYOXALATION OF VINYLAMIDE POLYMER THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2011-04-14 US disclosed
US-7875676-B2 Reacting substantially aqueous reaction mixture of a vinylamide polymer and a cellulose reactive agent to form the adduct,wherein concentration of vinylamide polymer is below, equal to or no more than 1% above a Critical Concentration of the vinylamide polymer; dry and wet strength aid for paper CIBA SPECIALTY CHEMICALS CORPORATION (US) 2011-01-25 US disclosed
US-20090223645-A1 Method and composition for improved temporary wet strength ZHANG NAIJIE 2009-09-10 US disclosed
US-20090126890-A1 Glyoxalated N-vinylamine THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2009-05-21 US disclosed
US-20090071618-A1 HIGH-PERFORMANCE STRENGTH RESINS IN PAPERMAKING INDUSTRIES KEMIRA OYJ (FI) 2009-03-19 US disclosed
US-20080108533-A1 Methacrylate copolymer pour point depressants CIBA CORP. 2008-05-08 US disclosed
US-20080064819-A1 Glyoxalation of vinylamide polymer THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2008-03-13 US disclosed
EP-1828479-A1 HIGH-PERFORMANCE STRENGTH RESINS IN PAPERMAKING INDUSTRIES Lanxess Corporation (US) 2007-09-05 EP disclosed
WO-2006016906-A1 HIGH-PERFORMANCE STRENGTH RESINS IN PAPERMAKING INDUSTRIES LANXESS CORPORATION (US) 2006-02-16 WO disclosed