Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 4/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | BMP4 | P12644 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.42 |
| ▸ | ABL2 | P42684 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295844 | 0.77 | NPC1 (0.46) | TGFBR1MAPK14CYP1A2NPC1RAB9A | |
| SCHEMBL8654587 | 0.77 | MAPT (0.43) | TGFBR1NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL27917128 | 0.77 | CYP1A2 (0.60) | TGFBR1MAPK14CYP1A2NPC1RAB9A | |
| SCHEMBL1227713 | 0.77 | CYP1A2 (0.60) | TGFBR1MAPK14CYP1A2NPC1RAB9A | |
| SCHEMBL29699887 | 0.77 | CYP1A2 (0.60) | TGFBR1MAPK14CYP1A2NPC1RAB9A | |
| SCHEMBL8096509 | 0.76 | CYP1A2 (0.49) | TGFBR1MAPK14CYP1A2NPC1RAB9A | |
| SCHEMBL30487734 | 0.75 | CYP1A2 (0.58) | TGFBR1MAPK14CYP1A2NPC1RAB9A | |
| SCHEMBL7918743 | 0.74 | MAPT (0.56) | TGFBR1MAPK14CYP1A2NPC1RAB9A | |
| SCHEMBL3422756 | 0.73 | CYP1A2 (0.54) | TGFBR1MAPK14CYP1A2NPC1RAB9A | |
| SCHEMBL6796273 | 0.72 | CYP1A2 (0.45) | TGFBR1MAPK14CYP1A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063956-A | APPLYING FUNGICIDE OR INSECTICIDE TO THE LOCUS WHERE CONTROL IS DESIRED | ROHM AND HAAS COMPANY (US) | 2000-05-16 | — | — | US | disclosed |