SCHEMBL8096638

SCHEMBL8096638

CBc1cc([C@H](C)NC(=O)CC(=O)Nc2ccc(C(=N)N)cc2)ccc1S(=O)(=O)N1CCOC(c2ccccc2)C1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F7 P08709 19/20 0.40
F2 P00734 13/20 0.40
F10 P00742 2/20 0.40
TPSAB1 Q15661 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL860520 0.90 F7 (0.47) F7F2F10
SCHEMBL860433 0.90 F7 (0.47) F7F2F10
SCHEMBL861128 0.78 F7 (0.49) F7F2F10
SCHEMBL860718 0.78 F7 (0.49) F7F2F10
SCHEMBL860708 0.78 F7 (0.50) F7F2F10
SCHEMBL878998 0.78 F7 (0.54) F7F2F10
SCHEMBL860543 0.76 F7 (0.53) F7F2F10
SCHEMBL861055 0.76 F7 (0.53) F7F2F10
SCHEMBL861298 0.76 F7 (0.60) F7F2F10
SCHEMBL861106 0.76 F7 (0.60) F7F2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009007015-A1 MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY SANOFI-AVENTIS (FR) 2009-01-15 WO disclosed