Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096843 | 1.00 | SLC6A4 (0.49) | SLC6A4SLC6A3SLC6A2POLBCYP3A4 | |
| SCHEMBL7828978 | 1.00 | SLC6A4 (0.49) | SLC6A4SLC6A3SLC6A2POLBCYP3A4 | |
| SCHEMBL7824679 | 0.82 | AKR1C3 (0.44) | POLBTSHRHSD17B10 | |
| SCHEMBL8706518 | 0.82 | AKR1C3 (0.44) | POLBTSHRHSD17B10 | |
| SCHEMBL8089414 | 0.82 | AKR1C3 (0.44) | POLBTSHRHSD17B10 | |
| SCHEMBL8096848 | 0.82 | AKR1C3 (0.44) | POLBTSHRHSD17B10 | |
| SCHEMBL8096658 | 0.82 | AKR1C3 (0.44) | POLBTSHRHSD17B10 | |
| SCHEMBL7828959 | 0.82 | AKR1C3 (0.44) | POLBTSHRHSD17B10 | |
| SCHEMBL8089417 | 0.82 | AKR1C3 (0.44) | POLBTSHRHSD17B10 | |
| SCHEMBL21768005 | 0.80 | PDE4B (0.47) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166037-A | Pyrrolidine and piperidine modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2000-12-26 | — | — | US | disclosed |