Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 12/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 10/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092240 | 1.00 | SRD5A1 (0.45) | SRD5A1SRD5A2CDK8 | |
| SCHEMBL8092265 | 0.85 | SRD5A1 (0.45) | SRD5A1SRD5A2 | |
| SCHEMBL8092260 | 0.85 | SRD5A1 (0.45) | SRD5A1SRD5A2 | |
| SCHEMBL8084004 | 0.85 | SRD5A1 (0.49) | SRD5A1SRD5A2 | |
| SCHEMBL8084007 | 0.85 | SRD5A1 (0.49) | SRD5A1SRD5A2 | |
| SCHEMBL8084014 | 0.81 | SRD5A1 (0.46) | SRD5A1SRD5A2 | |
| SCHEMBL8084018 | 0.81 | SRD5A1 (0.46) | SRD5A1SRD5A2 | |
| SCHEMBL8084472 | 0.80 | SRD5A1 (0.51) | SRD5A1SRD5A2 | |
| SCHEMBL8084476 | 0.80 | SRD5A1 (0.51) | SRD5A1SRD5A2 | |
| SCHEMBL8096725 | 0.79 | SRD5A1 (0.48) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756481-B1 | 17$g(b)-ARYL-4-AZA-STEROID DERIVATIVES | MERCK & CO INC (US) | 2000-12-27 | — | — | EP | claimed |