Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 16/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104996 | 0.87 | BRS3 (0.62) | BRS3CYP11B1CYP11B2HRH3 | |
| SCHEMBL7927590 | 0.86 | BRS3 (0.61) | BRS3HRH3PDE10A | |
| Hydrochloric Acid SCHEMBL8307429 | 0.86 | BRS3 (0.61) | BRS3CYP11B1CYP11B2HRH3 | |
| SCHEMBL7921316 | 0.86 | BRS3 (0.61) | BRS3CYP11B1CYP11B2HRH3 | |
| SCHEMBL7919370 | 0.85 | BRS3 (0.58) | BRS3HRH3PDE10A | |
| SCHEMBL7919393 | 0.85 | BRS3 (0.62) | BRS3CYP11B1CYP11B2HRH3 | |
| Hydrochloric Acid SCHEMBL8310488 | 0.84 | BRS3 (0.57) | BRS3HRH3PDE10A | |
| SCHEMBL8305740 | 0.84 | BRS3 (0.59) | BRS3CYP11B1CYP11B2HRH3 | |
| SCHEMBL8107240 | 0.84 | BRS3 (0.62) | BRS3PDE10A | |
| SCHEMBL8110784 | 0.84 | BRS3 (0.59) | BRS3HRH3PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986302-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-03-22 | — | — | EP | claimed |
| WO-1998054966-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1998-12-10 | — | — | WO | claimed |