Styrene

Styrene

SCHEMBL8097534

C=C(C)C(=O)O.C=CCOC(=O)C=C.C=Cc1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 2/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
MAPK1 P28482 1/20 0.47
CYP3A4 P08684 1/20 0.44
THRB P10828 1/20 0.43
ALDH1A1 P00352 5/20 0.40
TSHR P16473 3/20 0.40
HSD17B10 Q99714 3/20 0.40
ALOX12 P18054 1/20 0.40
PKM P14618 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
APP P05067 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CASP1 P29466 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL5460311 0.92 MAPT (0.42) MEN1KMT2AMAPTKDM4ELMNA
Styrene SCHEMBL3216401 0.92 MEN1 (0.45) MEN1KMT2AMAPTKDM4ELMNA
Styrene SCHEMBL167641 0.91 CYP3A4 (0.51) MEN1KMT2AMAPTKDM4ELMNA
Styrene SCHEMBL10786260 0.89 MAPT (0.44) MEN1KMT2AMAPTKDM4ELMNA
Styrene SCHEMBL11673981 0.89 MAPT (0.45) MEN1KMT2AMAPTKDM4ELMNA
Styrene SCHEMBL3117319 0.88 CYP3A4 (0.49) MEN1KMT2AMAPTKDM4ELMNA
Styrene SCHEMBL10822309 0.87 MAPT (0.42) MEN1KMT2AMAPTKDM4ELMNA
Styrene SCHEMBL8390268 0.87 MEN1 (0.46) MEN1KMT2AMAPTKDM4ELMNA
Styrene SCHEMBL9654658 0.86 CYP3A4 (0.44) MEN1KMT2AMAPTKDM4ELMNA
Styrene SCHEMBL10818757 0.85 CYP3A4 (0.46) MEN1KMT2AMAPTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808624-B1 Hair tonic KAO CORP (JP) 2000-12-06 EP disclosed
EP-0808624-A2 Hair tonic Kao Corporation (JP) 1997-11-26 EP disclosed
US-4814246-A Light-sensitive photoconductive recording material with light sensitive covering layer for use in manufacturing printing form or printed circuit HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-21 US disclosed
US-4680244-A Light-sensitive recording material for the production of a printing form or printed circuit with photoconductive layer and light-sensitive overlayer HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-14 US disclosed
US-4573782-A Developing apparatus for forming an image in light-sensitive material using photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1986-03-04 US disclosed
US-4500617-A ALUMINUM (OR ALLOY) SUPPORT, HYDROPHILIC ALUMINUM OXIDE, PHOTOSENSITIVE AND PHOTOCONDUCTIVE INSULATION LAYER FUJI PHOTO FILM CO., LTD. (JP) 1985-02-19 US disclosed