Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 10/20 | 0.64 |
| ▸ | ERAP2 | Q6P179 | 11/20 | 0.63 |
| ▸ | IL1RN | P18510 | 7/20 | 0.63 |
| ▸ | LNPEP | Q9UIQ6 | 6/20 | 0.61 |
| ▸ | TACR1 | P25103 | 3/20 | 0.58 |
| ▸ | NMBR | P28336 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15526241 | 1.00 | ERAP1 (0.64) | ERAP1ERAP2IL1RNLNPEPTACR1 | |
| SCHEMBL645270 | 0.94 | ERAP2 (0.59) | ERAP1ERAP2IL1RNLNPEPNMBR | |
| SCHEMBL27785996 | 0.93 | ERAP2 (0.59) | ERAP1ERAP2IL1RNLNPEPTACR1 | |
| SCHEMBL27785992 | 0.93 | ERAP2 (0.59) | ERAP1ERAP2IL1RNLNPEPTACR1 | |
| SCHEMBL4842606 | 0.90 | ERAP1 (0.63) | ERAP1ERAP2IL1RNLNPEPTACR1 | |
| SCHEMBL27764363 | 0.90 | ERAP1 (0.67) | ERAP1ERAP2IL1RNLNPEPTACR1 | |
| SCHEMBL27764365 | 0.90 | ERAP1 (0.67) | ERAP1ERAP2IL1RNLNPEPTACR1 | |
| SCHEMBL27855349 | 0.89 | ECE1 (0.55) | ERAP1ERAP2IL1RNLNPEPTACR1 | |
| SCHEMBL27871526 | 0.88 | ERAP1 (0.68) | ERAP1ERAP2IL1RNLNPEPTACR1 | |
| SCHEMBL28780567 | 0.87 | ERAP1 (0.59) | ERAP1ERAP2IL1RNLNPEPTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042286-A1 | GAMMA-GLUTAMYL AND BETA-ASPARTYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH | Wei, Edward T. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033799-A1 | GAMMA-GLUTAMYL AND BETA-ASPARTYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH | WEI EDWARD T (US) | 1999-07-08 | — | — | WO | disclosed |