SCHEMBL809774

SCHEMBL809774

CC(=O)C(C)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14339238 1.00
SCHEMBL805272 0.78
SCHEMBL1442241 0.75
SCHEMBL1033383 0.75
SCHEMBL583938 0.75
SCHEMBL135699 0.75
SCHEMBL1031171 0.75
SCHEMBL2185232 0.75
SCHEMBL21816671 0.75
SCHEMBL1695072 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2399895-B1 Process for producing optically active aliphatic fluoroalcohol KANTO KAGAKU (JP) 2018-08-08 EP disclosed
US-9845299-B2 Process for the preparation of a fluorolacton derivative GILEAD PHARMASSET LLC (US) 2017-12-19 US disclosed
US-9278935-B2 Method for preparing a fluorinated organic compound RHODIA OPERATIONS (FR) 2016-03-08 US disclosed
US-20150338736-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY- OR RADIATION-SENSITIVE FILM AND METHOD OF FORMING PATTERN FUJIFILM CORPORATION (JP) 2015-11-26 US disclosed
WO-2015027058-A2 CYCLOLKYL AMINE COMPOUNDS PREXA PHARMACEUTICALS, INC. (US) 2015-02-26 WO disclosed
US-20150057443-A1 Cycloalkyl Amine Compounds PREXA PHARMACEUTICALS, INC. 2015-02-26 US disclosed
US-20140148603-A1 Method for preparing a fluorinated organic compound RHODIA OPERATIONS (FR) 2014-05-29 US disclosed
US-20140065906-A1 SUPER HYDROPHOBIC MEMBRANE AND METHOD OF MANUFACTURING THE SAME SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2014-03-06 US disclosed
US-20140039153-A1 CANCER IMAGING AND TREATMENT TECHNISCHE UNIVERSITAT MUNCHEN (DE) 2014-02-06 US disclosed
US-20140039153-A1 CANCER IMAGING AND TREATMENT TECHNISCHE UNIVERSITAT MUNCHEN (DE) 2014-02-06 US disclosed
US-7834034-B2 Benzothiophene derivatives MERCK SHARP & DOHME CORP. (US) 2010-11-16 US disclosed
US-20100240072-A1 Cancer Imaging and Treatment TECHNISCHE UNIVERSITAT MUNCHEN (DE) 2010-09-23 US disclosed
US-20100087673-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE alpha-FLUOROCARBOXYLATE ESTER CENTRAL GLASS COMPANY, LTD (JP) 2010-04-08 US disclosed
US-20090082308-A1 Benzothiophene derivatives MERCK SHARP & DOHME LLC 2009-03-26 US disclosed
US-20090012075-A1 Fluorinated Arylamide Derivatives MERCK SHARP & DOHME CORP. 2009-01-08 US disclosed
US-7462734-B2 Industrial production of high purity drug and optical materials intermediates; reacting optically active alpha hydroxycarboxylate derivative with trifluoromethanesulfonyl fluoride in presence of organic base CENTRAL GLASS COMPANY, LIMITED (JP) 2008-12-09 US disclosed
US-20080145901-A1 NOVEL PROCESS FOR THE PREPARATION OF 3,5-DI-O-ACYL-2-FLUORO-2-C-METHYL-D-RIBONO-GAMMA-LACTONE CEDILOTE MIALL 2008-06-19 US disclosed
US-20080103327-A1 Industrial production of high purity drug and optical materials intermediates; reacting optically active alpha hydroxycarboxylate derivative with trifluoromethanesulfonyl fluoride in presence of organic base CENTRAL GLASS COMPANY, LIMITED (JP) 2008-05-01 US disclosed
US-20070287855-A1 Process for Preparing Fluorinated Molecules BAYER CROPSCIENCE AG (DE) 2007-12-13 US disclosed
US-4003807-A Electrochemical fluorination of ketones within the pores of an anode PHILLIPS PETROLEUM COMPANY (US) 1977-01-18 US disclosed