Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6255523 | 0.87 | MEN1 (0.56) | SLC6A2SLC6A4MEN1KMT2ACYP2D6 | |
| SCHEMBL5268174 | 0.75 | ESR1 (0.75) | SLC6A2SLC6A4MEN1KMT2ACHRNA7 | |
| SCHEMBL8097776 | 0.74 | CHRNA7 (0.79) | SLC6A2SLC6A4MEN1KMT2ACHRNA7 | |
| SCHEMBL8963664 | 0.73 | MEN1 (0.56) | SLC6A2SLC6A4MEN1KMT2ACYP2D6 | |
| SCHEMBL9818808 | 0.71 | CYP2D6 (0.53) | SLC6A2SLC6A4MEN1KMT2ACHRNA7 | |
| SCHEMBL4189112 | 0.70 | SLC6A2 (0.48) | SLC6A2SLC6A4CHRNA7ESR1CYP2D6 | |
| SCHEMBL42790 | 0.69 | CYP2D6 (0.73) | SLC6A2SLC6A4MEN1KMT2ACYP2D6 | |
| SCHEMBL3950480 | 0.69 | CYP2D6 (0.73) | SLC6A2SLC6A4MEN1KMT2ACYP2D6 | |
| SCHEMBL3956861 | 0.69 | CYP2D6 (0.73) | SLC6A2SLC6A4MEN1KMT2ACYP2D6 | |
| SCHEMBL7451551 | 0.68 | MEN1 (0.50) | SLC6A2SLC6A4MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983222-A1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORPORATION (CA) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052898-A9 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORP (CA) | 1999-04-01 | — | — | WO | disclosed |
| WO-1998052898-A1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORPORATION (CA) | 1998-11-26 | — | — | WO | disclosed |