Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.53 |
| ▸ | FNTB | P49356 | 15/20 | 0.53 |
| ▸ | PGGT1B | P53609 | 13/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097918 | 1.00 | FNTA (0.53) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8104375 | 0.95 | FNTA (0.50) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8104368 | 0.95 | FNTA (0.50) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8095947 | 0.95 | CYP11B1 (0.54) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8095950 | 0.95 | CYP11B1 (0.54) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8097899 | 0.93 | FNTA (0.57) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8097904 | 0.93 | FNTA (0.57) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8101710 | 0.92 | FNTA (0.55) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8101714 | 0.92 | FNTA (0.55) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8088331 | 0.90 | FNTA (0.52) | FNTAFNTBPGGT1BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |