⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2440141 | 0.81 | ACACB (0.34) | — | |
| SCHEMBL8104959 | 0.78 | ACACB (0.33) | — | |
| SCHEMBL8098245 | 0.73 | ACACB (0.30) | — | |
| SCHEMBL8098363 | 0.72 | CHRM2 (0.32) | — | |
| SCHEMBL7782432 | 0.70 | ACACB (0.33) | — | |
| SCHEMBL8097956 | 0.70 | ACACB (0.36) | — | |
| SCHEMBL7787271 | 0.70 | ACACB (0.33) | — | |
| SCHEMBL7790221 | 0.68 | ACACB (0.33) | — | |
| SCHEMBL7790227 | 0.65 | PIK3CD (0.31) | — | |
| SCHEMBL2785153 | 0.65 | ACACB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885933-B1 | One-component alkoxy containing RTV-silicone rubber compositions | WACKER CHEMIE GMBH (DE) | 2000-08-30 | — | — | EP | disclosed |
| US-6020449-A | Alkoxy-crosslinking RTV1 silicone rubber mixtures | WACKER-CHEMIE GMBH (DE) | 2000-02-01 | — | — | US | disclosed |
| US-6018011-A | OBTAINED BY REACTING A POLYORGANOSILOXANE, WITH A REACTION PRODUCT OF AN ORGANOSILANE OF GIVEN FORMULA AND N-1-((METHYLDIETHOXYSILOXY)DIETHOXYSILYL)ETHYL-2-PYRROLIDONE; USE IN ALKOXY-CROSSLINKING RTV SILICONE RUBBER MIXTURES | HUELS SILICONE GMBH (DE) | 2000-01-25 | — | — | US | disclosed |
| US-6001948-A | BASED ON HYDROXY-TERMINATED POLYDIORGANOSILOXANES CONTAINING A TRIALKOXYSILANE WITH A SUBSTITUTED AMIDOALKYL RADICAL, WHICH CAN BE PREPARED USING CONVENTIONAL MIXING TECHNOLOGIES. | WACKER-CHEMIE GMBH (DE) | 1999-12-14 | — | — | US | disclosed |
| EP-0885931-A2 | One-component alkoxy group containing RTV-systems | Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0885915-A2 | Polyorganosiloxanes having dialkoxyorganosiloxy groups | Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0885933-A1 | One-component alkoxy containing RTV-silicone rubber compositions | Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) | 1998-12-23 | — | — | EP | disclosed |