Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.30 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104772 | 0.83 | CYP3A4 (0.32) | — | |
| SCHEMBL29284609 | 0.77 | PDPK1 (0.31) | PDPK1 | |
| SCHEMBL2137200 | 0.77 | DYRK1A (0.44) | CXCR1CXCR2LMNA | |
| SCHEMBL16960784 | 0.77 | PDPK1 (0.31) | PDPK1 | |
| SCHEMBL31156147 | 0.77 | DYRK1A (0.44) | CXCR1CXCR2LMNA | |
| SCHEMBL95210 | 0.76 | TSHR (0.42) | LMNA | |
| SCHEMBL94460 | 0.76 | GAA (0.33) | — | |
| SCHEMBL95291 | 0.75 | — | — | |
| SCHEMBL9242790 | 0.74 | — | — | |
| SCHEMBL2783652 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096920-A | LARGE-SCALE PRODUCTION OF CERTAIN AROMATICALLY-SUBSTITUTED ALIPHATIC CARBOXYLIC ACIDS AND THEIR ACID DERIVATIVES | ALBEMARLE CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |