Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099834 | 1.00 | CNR1 (0.46) | CNR1CNR2TLR8KCNH2GPR3 | |
| SCHEMBL8086350 | 1.00 | CNR1 (0.46) | CNR1CNR2TLR8KCNH2GPR3 | |
| SCHEMBL8087092 | 0.99 | CNR1 (0.46) | CNR1CNR2TLR8LTA4H | |
| SCHEMBL8087103 | 0.96 | CNR1 (0.48) | CNR1CNR2TLR8GPR3LIPG | |
| SCHEMBL8102084 | 0.96 | CNR1 (0.48) | CNR1CNR2TLR8GPR3LIPG | |
| SCHEMBL8094871 | 0.96 | CNR1 (0.48) | CNR1CNR2TLR8GPR3LIPG | |
| SCHEMBL8095605 | 0.94 | CNR1 (0.42) | CNR1CNR2TLR8LTA4H | |
| SCHEMBL8095568 | 0.94 | CNR1 (0.49) | CNR1CNR2TLR8LIPGLTA4H | |
| SCHEMBL8102345 | 0.92 | CNR1 (0.47) | CNR1CNR2TLR8GPR3LIPG | |
| SCHEMBL8099385 | 0.92 | CNR1 (0.47) | CNR1CNR2TLR8GPR3LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |