Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094269 | 0.91 | SRD5A2 (0.67) | SRD5A2LMNAGAATSHRL3MBTL1 | |
| SCHEMBL9146746 | 0.89 | KCNH2 (0.56) | SRD5A2LMNAGAATSHRL3MBTL1 | |
| SCHEMBL18913824 | 0.85 | TSHR (0.69) | TSHRPOLBALDH1A1KCNH2KCNJ1 | |
| SCHEMBL13719703 | 0.85 | SRD5A2 (0.59) | SRD5A2LMNAGAATSHRL3MBTL1 | |
| SCHEMBL8095914 | 0.84 | SRD5A2 (0.67) | SRD5A2LMNAGAATSHRL3MBTL1 | |
| SCHEMBL8094198 | 0.84 | SRD5A2 (0.67) | SRD5A2LMNAGAATSHRL3MBTL1 | |
| SCHEMBL9018930 | 0.84 | SRD5A2 (0.67) | SRD5A2LMNAGAATSHRL3MBTL1 | |
| SCHEMBL8094425 | 0.84 | SRD5A2 (0.67) | SRD5A2LMNAGAATSHRL3MBTL1 | |
| SCHEMBL10723714 | 0.83 | SRD5A2 (0.83) | SRD5A2LMNAGAATSHRL3MBTL1 | |
| SCHEMBL975118 | 0.83 | SRD5A2 (0.83) | SRD5A2LMNAGAATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |