SCHEMBL8100394

SCHEMBL8100394

CC1=NC=C(O)C(=O)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7934354 0.70
SCHEMBL9012925 0.69 KDM4E (0.31)
SCHEMBL8077722 0.68
SCHEMBL8100816 0.65
SCHEMBL14461287 0.62
SCHEMBL8102110 0.60 TYR (0.33)
SCHEMBL2708576 0.60
SCHEMBL17808207 0.59
SCHEMBL6454780 0.57
SCHEMBL4414023 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE36831-E TREATMENT OF IRON DEFICIENCY ANEMIA BRITISH TECHNOLOGY GROUP LTD. (GB) 2000-08-22 US claimed
US-5962480-A CONTAINING PYRAN-4-ONE OR PYRID-4-ONE RING WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 1999-10-05 US claimed
US-RE35948-E TREATING TOXIC METAL CONCENTRATION BY ADMINISTERING N-SUBSTITUTED 3-HYDROXYPYRID-2-ONE OR 3-HYDROXYPYRID-4-ONE BRITISH TECHNOLOGY GROUP LTD. (GB) 1998-11-03 US claimed
EP-0305646-A2 3-Hydroxypyrid-4-ones and pharmaceutical compositions BTG INTERNATIONAL LIMITED (GB) 1989-03-08 EP claimed
US-4650793-A NITROGEN-SUBSTITUTED NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1987-03-17 US claimed
US-4585780-A CHELATION OF HEAVY METALS IN BLOOD NATIONAL RESEARCH DEVELOPMENT CORP. (GB) 1986-04-29 US claimed
EP-0120669-A2 Hydroxypyridones, and their pharmaceutical compositions NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-10-03 EP claimed
EP-0120670-A1 Iron III complexes of hydroxypyridones, and their pharmaceutical compositions NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-10-03 EP claimed
US-5962480-A CONTAINING PYRAN-4-ONE OR PYRID-4-ONE RING WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 1999-10-05 US disclosed
EP-0838220-A1 DRUG FOR AMELIORATING BRAIN DISEASES WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 1998-04-29 EP disclosed
CN-1025737-C Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1994-08-24 CN disclosed
CN-1038814-A Cephem compound and preparation method thereof FUJISAWA PHARMACEUTICAL CO (JP) 1990-01-17 CN disclosed