Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099319 | 0.93 | GSK3B (0.75) | GSK3B | |
| SCHEMBL12873995 | 0.90 | GSK3B (0.71) | GSK3B | |
| SCHEMBL8084992 | 0.88 | GSK3B (0.75) | GSK3B | |
| SCHEMBL8091849 | 0.88 | GSK3B (0.78) | GSK3B | |
| SCHEMBL1185915 | 0.87 | GSK3B (0.72) | GSK3B | |
| SCHEMBL1186415 | 0.87 | GSK3B (0.70) | GSK3B | |
| SCHEMBL8090206 | 0.87 | GSK3B (0.68) | GSK3B | |
| SCHEMBL17586332 | 0.86 | GSK3B (0.67) | GSK3B | |
| SCHEMBL1186244 | 0.86 | GSK3B (1.00) | GSK3B | |
| SCHEMBL1186828 | 0.85 | GSK3B (0.68) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009035684-A1 | SPIROCYCLIC AMINOQUINOLONES AS GSK-3 INHIBITORS | ACTIVX BIOSCIENCES, INC. (US) | 2009-03-19 | — | — | WO | disclosed |