Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107512 | 1.00 | TDP1 (0.60) | TDP1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL8100999 | 1.00 | TDP1 (0.60) | TDP1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL8100611 | 1.00 | TDP1 (0.60) | TDP1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL8101619 | 1.00 | TDP1 (0.60) | TDP1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL8105240 | 1.00 | TDP1 (0.60) | TDP1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL8107491 | 1.00 | TDP1 (0.60) | TDP1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL8099312 | 0.98 | TDP1 (0.58) | TDP1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL8098655 | 0.94 | TDP1 (0.51) | TDP1L3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL2398501 | 0.87 | GLA (0.52) | TDP1L3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL9276798 | 0.82 | TDP1 (0.47) | TDP1L3MBTL1MEN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166003-A | Heterocyclic compounds for cancer chemoprevention | LKT LABORATORIES, INC. (US) | 2000-12-26 | — | — | US | disclosed |
| WO-2000049013-A1 | ISOTHIO CYANATO ALKYLTHIOPHENES AS CANCER CHEMOPROTECTIVE AGENTS | LKT LABORATORIES, INC. (US) | 2000-08-24 | — | — | WO | disclosed |