Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | GALR3 | O60755 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | GUSB | P08236 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4855474 | 0.84 | HTT (0.75) | HTTKMT2AMEN1RAB9AGALR3 | |
| SCHEMBL5053541 | 0.83 | HTT (0.73) | HTTKMT2AMEN1RAB9AGALR3 | |
| SCHEMBL4852085 | 0.83 | HTT (0.73) | HTTKMT2AMEN1RAB9AGALR3 | |
| SCHEMBL3924829 | 0.82 | HTT (0.75) | HTTKMT2AMEN1RAB9AGALR3 | |
| SCHEMBL6586520 | 0.79 | IGF1R (0.79) | HTTKMT2AMEN1RAB9AGALR3 | |
| SCHEMBL8402836 | 0.79 | HTT (0.75) | HTTKMT2AMEN1RAB9AGALR3 | |
| SCHEMBL13609778 | 0.78 | HTT (0.66) | HTTKMT2AMEN1RAB9AGALR3 | |
| SCHEMBL19308467 | 0.78 | HTT (0.73) | HTTKMT2AMEN1RAB9AGALR3 | |
| SCHEMBL4872495 | 0.78 | HTT (0.73) | HTTKMT2AMEN1RAB9AGALR3 | |
| SCHEMBL6586139 | 0.78 | HTT (0.66) | HTTKMT2AMEN1RAB9AGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HAT1 | HTT 711/4885KMT2A 37/4885MEN1 3832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.