Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HRH1 | P35367 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094152 | 1.00 | CYP19A1 (0.45) | CYP19A1HTR2AHRH1MAPTSIGMAR1 | |
| SCHEMBL12112001 | 0.96 | CYP19A1 (0.47) | CYP19A1HTR2AHRH1MAPTSIGMAR1 | |
| SCHEMBL8101640 | 0.96 | CYP19A1 (0.47) | CYP19A1HTR2AHRH1MAPTSIGMAR1 | |
| SCHEMBL8086062 | 0.94 | CYP19A1 (0.44) | CYP19A1HTR2AHRH1MAPTSIGMAR1 | |
| SCHEMBL8086523 | 0.94 | CYP19A1 (0.44) | CYP19A1HTR2AHRH1MAPTSIGMAR1 | |
| SCHEMBL8101488 | 0.92 | CYP19A1 (0.43) | CYP19A1HTR2AHRH1MAPTSIGMAR1 | |
| SCHEMBL8099445 | 0.92 | CYP19A1 (0.43) | CYP19A1HTR2AHRH1MAPTSIGMAR1 | |
| SCHEMBL8094205 | 0.92 | CYP19A1 (0.43) | CYP19A1HTR2AHRH1MAPTSIGMAR1 | |
| SCHEMBL8094749 | 0.92 | CYP19A1 (0.43) | CYP19A1HTR2AHRH1MAPTSIGMAR1 | |
| SCHEMBL8095178 | 0.92 | CYP19A1 (0.43) | CYP19A1HTR2AHRH1MAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |