Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4110616 | 1.00 | FDFT1 (0.44) | FDFT1POLB | |
| SCHEMBL8110789 | 0.90 | FDFT1 (0.48) | FDFT1 | |
| SCHEMBL4110079 | 0.90 | FDFT1 (0.48) | FDFT1 | |
| SCHEMBL4112897 | 0.90 | FDFT1 (0.38) | FDFT1 | |
| SCHEMBL8116382 | 0.90 | FDFT1 (0.38) | FDFT1 | |
| SCHEMBL8111693 | 0.89 | FDFT1 (0.41) | FDFT1POLB | |
| SCHEMBL8636201 | 0.89 | FDFT1 (0.43) | FDFT1 | |
| SCHEMBL8636205 | 0.89 | FDFT1 (0.43) | FDFT1 | |
| SCHEMBL8636199 | 0.89 | FDFT1 (0.43) | FDFT1 | |
| SCHEMBL8118252 | 0.89 | FDFT1 (0.53) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645378-B1 | Condensed seven- or eight-membered heterocyclic compounds useful as squalene synthetase inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-08-23 | — | — | EP | claimed |
| JP-7179429-A | — | — | None | — | — | JP | disclosed |
| EP-0645378-B1 | Condensed seven- or eight-membered heterocyclic compounds useful as squalene synthetase inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5698691-A | ANTICHOLESTEROL AGENT; SYNTHETASE INHIBITOR; FUNGICIDE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| JP-H07179429-A | CONDENSED RING COMPOUND AND ITS USE | TAKEDA CHEM IND LTD | 1995-07-18 | — | — | JP | disclosed |
| EP-0645378-A1 | Condensed seven- or eight-membered heterocyclic compounds useful as squalene synthetase inhibitors | Takeda Chemical Industries, Ltd. (JP) | 1995-03-29 | — | — | EP | disclosed |