Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13945379 | 0.89 | EHMT2 (0.47) | EHMT2ACHEKMT2ASCN1ASCN8A | |
| SCHEMBL4241073 | 0.88 | CHRM4 (0.42) | ACHEPDE4B | |
| SCHEMBL4245783 | 0.88 | CCR3 (0.45) | KMT2APDE4BMEN1 | |
| SCHEMBL4249178 | 0.87 | CCR3 (0.42) | EHMT2KMT2APDE4BMEN1 | |
| SCHEMBL4241800 | 0.84 | PDE4B (0.37) | EHMT2ACHEKMT2APDE4BMEN1 | |
| SCHEMBL8095680 | 0.77 | PDE4B (0.46) | EHMT2ACHEKMT2APDE4BSCN1A | |
| SCHEMBL8102582 | 0.76 | DPP4 (0.49) | ACHEKMT2AMEN1DRD4 | |
| SCHEMBL8100440 | 0.76 | PDE4B (0.35) | EHMT2ACHEKMT2APDE4BSCN1A | |
| SCHEMBL8094318 | 0.75 | SMN1; SMN2 (0.51) | EHMT2ACHEKMT2ASCN1ASCN8A | |
| SCHEMBL5529538 | 0.74 | PDE4B (0.46) | EHMT2ACHEKMT2APDE4BSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000085-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-12-31 | — | — | WO | disclosed |