Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.48 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.44 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MECP2 | P51608 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106567 | 1.00 | HDAC6 (0.48) | HDAC6NLNHDAC4MEF2DEP300 | |
| SCHEMBL14345655 | 0.87 | HDAC4 (0.50) | HDAC6HDAC4MEF2DEP300SLC40A1 | |
| SCHEMBL8118881 | 0.87 | HDAC4 (0.50) | HDAC6HDAC4MEF2DEP300SLC40A1 | |
| SCHEMBL5466442 | 0.87 | HDAC1 (0.50) | HDAC6HDAC4MEF2DEP300SLC40A1 | |
| SCHEMBL5327739 | 0.87 | KDM4E (0.50) | HDAC6NLNHDAC4MEF2DEP300 | |
| SCHEMBL5327734 | 0.87 | KDM4E (0.50) | HDAC6NLNHDAC4MEF2DEP300 | |
| SCHEMBL5329359 | 0.86 | HDAC6 (0.53) | HDAC6NLNHDAC4MEF2DEP300 | |
| SCHEMBL8117546 | 0.86 | NPY5R (0.46) | HDAC6CA12CA1CA7CA14 | |
| SCHEMBL8118903 | 0.83 | HDAC1 (0.65) | HDAC6HDAC4MEF2DEP300HDAC1 | |
| SCHEMBL14345654 | 0.83 | HDAC1 (0.65) | HDAC6HDAC4MEF2DEP300HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-20 | — | — | US | disclosed |
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HAT1 | HDAC6 11/4885NLN 4696/4885HDAC4 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.