Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.57 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161936 | 0.78 | CSNK1E (0.71) | CSNK1ESIGMAR1 | |
| SCHEMBL8420654 | 0.78 | CSNK1E (0.71) | CSNK1ESIGMAR1 | |
| SCHEMBL1829488 | 0.78 | CSNK1E (0.71) | CSNK1ESIGMAR1 | |
| SCHEMBL10399079 | 0.78 | CSNK1E (0.71) | CSNK1ESIGMAR1 | |
| SCHEMBL4878177 | 0.78 | CSNK1E (0.71) | CSNK1ESIGMAR1 | |
| SCHEMBL873387 | 0.78 | CSNK1E (0.71) | CSNK1ESIGMAR1 | |
| SCHEMBL11455433 | 0.78 | CSNK1E (0.71) | CSNK1ESIGMAR1 | |
| SCHEMBL9485679 | 0.78 | KCNH2 (0.66) | KCNH2SIGMAR1MAPT | |
| SCHEMBL1262348 | 0.78 | KCNH2 (0.66) | KCNH2SIGMAR1MAPT | |
| SCHEMBL9485273 | 0.78 | KCNH2 (0.66) | KCNH2SIGMAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |