Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.80 |
| ▸ | HDAC1 | Q13547 | 17/20 | 0.80 |
| ▸ | HDAC3 | O15379 | 16/20 | 0.79 |
| ▸ | HDAC4 | P56524 | 16/20 | 0.79 |
| ▸ | HDAC7 | Q8WUI4 | 16/20 | 0.79 |
| ▸ | HDAC2 | Q92769 | 16/20 | 0.79 |
| ▸ | HDAC10 | Q969S8 | 16/20 | 0.79 |
| ▸ | HDAC11 | Q96DB2 | 16/20 | 0.79 |
| ▸ | HDAC8 | Q9BY41 | 16/20 | 0.79 |
| ▸ | HDAC9 | Q9UKV0 | 16/20 | 0.79 |
| ▸ | HDAC5 | Q9UQL6 | 16/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327667 | 0.92 | HDAC6 (0.82) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5328254 | 0.91 | HDAC6 (0.81) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL8119260 | 0.91 | HDAC6 (0.79) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5468800 | 0.91 | HDAC6 (0.85) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5468805 | 0.91 | HDAC6 (0.85) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5330036 | 0.89 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5330042 | 0.89 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5459414 | 0.88 | HDAC6 (0.73) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL8118753 | 0.88 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5324599 | 0.88 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HAT1 | HDAC6 11/4885HDAC1 1/4885HDAC3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.