Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512456 | 0.88 | CA1 (0.39) | CA1CA2CA7CA9CA12 | |
| SCHEMBL22100451 | 0.80 | CA1 (0.65) | CA1CA2CA7CA9CA12 | |
| 1,4-Dimethoxybenzene SCHEMBL8489 | 0.78 | CA1 (1.00) | CA1CA2CA7CA9CA12 | |
| 1,4-Dimethoxybenzene SCHEMBL21802643 | 0.78 | CA1 (1.00) | CA1CA2CA7CA9CA12 | |
| 1,4-Dimethoxybenzene SCHEMBL30704776 | 0.75 | CA1 (0.92) | CA1CA2CA7CA9CA12 | |
| 1,4-Dimethoxybenzene SCHEMBL29937047 | 0.75 | CA1 (0.92) | CA1CA2CA7CA9CA12 | |
| 1,4-Dimethoxybenzene SCHEMBL28244984 | 0.75 | CA1 (0.92) | CA1CA2CA7CA9CA12 | |
| 1,4-Dimethoxybenzene SCHEMBL27866971 | 0.75 | CA1 (0.92) | CA1CA2CA7CA9CA12 | |
| 1,4-Dimethoxybenzene SCHEMBL27892470 | 0.75 | CA1 (0.92) | CA1CA2CA7CA9CA12 | |
| 1,4-Dimethoxybenzene SCHEMBL28282673 | 0.75 | CA1 (0.92) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112851656-B | Lactam compound derivative and application thereof | 江苏恩华药业股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-112851656-A | Lactam compound derivative and application thereof | 江苏恩华药业股份有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-108290880-B | Lactam compound derivative and application thereof | 江苏恩华药业股份有限公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-108290880-A | LACTAM COMPOUND DERIVATIVE AND APPLICATION THEREOF | 江苏恩华药业股份有限公司 | 2018-07-17 | — | — | CN | disclosed |
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |