Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.56 |
| ▸ | RAF1 | P04049 | 3/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.56 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812847 | 0.99 | MAPK14 (0.54) | MAPK14MAPK13RAF1MAPK9MAPK12 | |
| SCHEMBL8120061 | 0.95 | MAPK14 (0.55) | MAPK14MAPK13RAF1MAPK9MAPK12 | |
| SCHEMBL4586526 | 0.91 | MAPK14 (0.61) | MAPK14MAPK13RAF1MAPK9MAPK12 | |
| SCHEMBL4583055 | 0.90 | MAPK14 (0.61) | MAPK14MAPK13RAF1MAPK9MAPK12 | |
| SCHEMBL4585291 | 0.90 | MAPK14 (0.63) | MAPK14MAPK13RAF1MAPK9MAPK12 | |
| SCHEMBL4584142 | 0.88 | MAPK14 (0.63) | MAPK14MAPK13RAF1MAPK9MAPK12 | |
| SCHEMBL4584672 | 0.86 | MAPK14 (0.60) | MAPK14MAPK13RAF1MAPK9MAPK12 | |
| SCHEMBL8108398 | 0.86 | MAPK14 (0.60) | MAPK14MAPK13RAF1MAPK9MAPK12 | |
| SCHEMBL8099919 | 0.86 | MAPK14 (0.60) | MAPK14MAPK13RAF1MAPK9MAPK12 | |
| SCHEMBL8108392 | 0.85 | MAPK14 (0.58) | MAPK14MAPK13RAF1MAPK9MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021173-A1 | USE OF CSAID?TM COMPOUNDS FOR THE MANAGEMENT OF UTERINE CONTRACTIONS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999018942-A1 | USE OF CSAIDTM COMPOUNDS FOR THE MANAGEMENT OF UTERINE CONTRACTIONS | IMPERIAL COLLEGE INNOVATIONS LTD. (GB) | 1999-04-22 | — | — | WO | disclosed |