Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.89 |
| ▸ | PPARD | Q03181 | 5/20 | 0.89 |
| ▸ | PPARA | Q07869 | 5/20 | 0.89 |
| ▸ | F7 | P08709 | 5/20 | 0.89 |
| ▸ | F3 | P13726 | 5/20 | 0.89 |
| ▸ | TERT | O14746 | 3/20 | 0.89 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.89 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.89 |
| ▸ | FABP4 | P15090 | 3/20 | 0.89 |
| ▸ | TOP1 | P11387 | 3/20 | 0.89 |
| ▸ | MAPT | P10636 | 2/20 | 0.89 |
| ▸ | BLM | P54132 | 2/20 | 0.89 |
| ▸ | LMNA | P02545 | 2/20 | 0.89 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.89 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.89 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.89 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.89 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.89 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.89 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleic Acid SCHEMBL11494840 | 1.00 | PPARG (0.89) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL27816432 | 0.98 | PPARG (0.92) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL27890987 | 0.98 | PPARG (0.92) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL29601875 | 0.98 | PPARG (0.92) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL3751821 | 0.98 | PPARG (0.92) | PPARGPPARDPPARAF7F3 | |
| Erucic Acid SCHEMBL6561087 | 0.98 | PPARG (0.92) | PPARGPPARDPPARAF7F3 | |
| Nervonic Acid SCHEMBL27652694 | 0.98 | PPARG (0.92) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL28288665 | 0.96 | PPARG (0.89) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL28445727 | 0.96 | PPARG (0.89) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL10483175 | 0.96 | PPARG (0.96) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130190-A | PERPENDICULAR ALIGNING SURFACTANT | PENNZOIL PRODUCTS COMPANY (US) | 2000-10-10 | — | — | US | disclosed |
| WO-1999024533-A1 | LIQUID CRYSTAL AND SURFACTANT CONTAINING LUBRICANT COMPOSITIONS | PENNZOIL QUAKER STATE COMPANY (US) | 1999-05-20 | — | — | WO | disclosed |