Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1651880 | 0.81 | CYP3A4 (0.46) | CYP3A4CYP2C9CYP2C19GAASMN1; SMN2 | |
| SCHEMBL1278020 | 0.80 | GAA (0.40) | CYP3A4CYP2C9CYP2C19GAASMN1; SMN2 | |
| SCHEMBL16979607 | 0.79 | CYP3A4 (0.38) | CYP3A4CYP2C9CYP2C19GAASMN1; SMN2 | |
| SCHEMBL11085863 | 0.79 | CYP2C9 (0.38) | CYP3A4CYP2C9CYP2C19GAASMN1; SMN2 | |
| SCHEMBL7474281 | 0.79 | CYP2C9 (0.38) | CYP3A4CYP2C9CYP2C19GAASMN1; SMN2 | |
| SCHEMBL5575508 | 0.79 | CYP3A4 (0.38) | CYP3A4CYP2C9CYP2C19GAASMN1; SMN2 | |
| SCHEMBL4922746 | 0.77 | GAA (0.38) | CYP3A4CYP2C9CYP2C19GAASMN1; SMN2 | |
| SCHEMBL9325074 | 0.76 | CYP3A4 (0.42) | CYP3A4CYP2C9CYP2C19GAASMN1; SMN2 | |
| SCHEMBL11566332 | 0.76 | CYP3A4 (0.42) | CYP3A4CYP2C9CYP2C19GAASMN1; SMN2 | |
| SCHEMBL13269359 | 0.76 | POLB (0.38) | CYP3A4CYP2C9CYP2C19GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057995-C | Substituted ortho-ethenylphenylacetic acid derivatives | BSAF AG (DE) | 2000-11-01 | — | — | CN | disclosed |
| US-6096895-A | Heterocyclic dihydrazole compounds and their use for controlling fungal plant diseases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-01 | — | — | US | disclosed |
| US-6057352-A | CONTROLLING PLANT DISEASES CAUSED BY FUNGAL PLANT PATHOGENS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0825992-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-03-04 | — | — | EP | disclosed |
| US-5686461-A | INHIBITION OF NMDA INDUCED CONVULSIONS | GLAXO WELLCOME S.P.A. (IT) | 1997-11-11 | — | — | US | disclosed |
| US-5633268-A | FUNGICIDES, INSECTICIDES, PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |
| WO-1996036633-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-11-21 | — | — | WO | disclosed |