Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 9/20 | 0.60 |
| ▸ | TOP2B | Q02880 | 9/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545104 | 0.89 | TOP2A (0.61) | TOP2ATOP2BL3MBTL1KDM4EKDM1A | |
| SCHEMBL3986033 | 0.88 | TOP2A (0.60) | TOP2ATOP2BKMT2AHDAC3HDAC4 | |
| SCHEMBL4257864 | 0.87 | TOP2A (0.61) | TOP2ATOP2BL3MBTL1KDM4EKDM1A | |
| SCHEMBL5404447 | 0.84 | TOP2A (0.66) | TOP2ATOP2BL3MBTL1KDM4EKDM1A | |
| SCHEMBL3989825 | 0.84 | TOP2A (0.66) | TOP2ATOP2BL3MBTL1KDM4EKDM1A | |
| SCHEMBL8104139 | 0.84 | TOP2A (0.60) | TOP2ATOP2BL3MBTL1KDM4EKDM1A | |
| SCHEMBL9299772 | 0.84 | TOP2A (0.62) | TOP2ATOP2BL3MBTL1KDM4EKDM1A | |
| SCHEMBL3984667 | 0.82 | TOP2A (0.64) | TOP2ATOP2BL3MBTL1KDM4EKDM1A | |
| SCHEMBL9300052 | 0.81 | TOP2A (0.73) | TOP2ATOP2BL3MBTL1KDM4EKDM1A | |
| SCHEMBL6545808 | 0.80 | TOP2A (0.58) | TOP2ATOP2BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1062207-A1 | 9-AMINOACRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2000-12-27 | — | — | EP | disclosed |
| WO-2000037447-A1 | 9-AMINOACRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-06-29 | — | — | WO | disclosed |