Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93076 | 0.94 | KDM4E (0.43) | S1PR1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL80241 | 0.83 | PDK2 (0.35) | S1PR1KDM4EALDH1A1RAB9APDK2 | |
| SCHEMBL81594 | 0.83 | NPC1 (0.42) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL81080 | 0.81 | PDK2 (0.36) | PDK2KMT2A | |
| SCHEMBL80998 | 0.81 | PDK2 (0.36) | PDK2KMT2A | |
| SCHEMBL81005 | 0.80 | PDK2 (0.37) | PDK2 | |
| SCHEMBL80234 | 0.80 | PDK2 (0.37) | PDK2 | |
| SCHEMBL80301 | 0.80 | KMT2A (0.34) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL81600 | 0.79 | PDK2 (0.35) | PDK2KMT2A | |
| SCHEMBL81002 | 0.79 | PDK2 (0.33) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129899-B1 | Azafluorene derivative and organic light-emitting device using the derivative | CANON KABUSHIKI KAISHA (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20120049176-A1 | AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |