Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 19/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13137296 | 0.80 | CD38 (0.60) | CD38CYP3A4KCNH2 | |
| SCHEMBL3048201 | 0.79 | CD38 (0.67) | CD38CYP3A4KCNH2NR4A2 | |
| SCHEMBL3055102 | 0.78 | CD38 (0.62) | CD38CYP3A4KCNH2NR4A2 | |
| SCHEMBL3056630 | 0.78 | CD38 (0.71) | CD38CYP3A4KCNH2 | |
| SCHEMBL3060907 | 0.76 | CD38 (0.64) | CD38CYP3A4KCNH2NR4A2 | |
| SCHEMBL3058765 | 0.75 | CD38 (0.67) | CD38CYP3A4KCNH2NR4A2 | |
| SCHEMBL3055096 | 0.73 | CD38 (0.73) | CD38CYP3A4KCNH2NR4A2 | |
| SCHEMBL3056839 | 0.73 | CD38 (0.62) | CD38CYP3A4KCNH2 | |
| SCHEMBL8106886 | 0.72 | CD38 (0.69) | CD38CYP3A4KCNH2NR4A2 | |
| SCHEMBL3050042 | 0.72 | CD38 (0.72) | CD38CYP3A4KCNH2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009024611-A2 | 4-BENZYLAMINOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | ABBOTT GMBH & CO. KG (DE) | 2009-02-26 | — | — | WO | disclosed |