Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3103821 | 0.85 | NOTUM (0.58) | NOTUMKDM4EALDH1A1MAPK1PDK2 | |
| SCHEMBL18725354 | 0.84 | NOTUM (0.58) | NOTUMKDM4EALDH1A1MAPK1PDK2 | |
| SCHEMBL1353718 | 0.81 | NOTUM (0.49) | NOTUMKDM4EALDH1A1MAPK1PDK2 | |
| SCHEMBL7027881 | 0.81 | NOTUM (0.49) | NOTUMKDM4EALDH1A1MAPK1PDK2 | |
| SCHEMBL7027887 | 0.81 | NOTUM (0.49) | NOTUMKDM4EALDH1A1MAPK1PDK2 | |
| Hydrochloric Acid SCHEMBL17389322 | 0.79 | NOTUM (0.47) | NOTUMKDM4EALDH1A1MAPK1PDK2 | |
| SCHEMBL8202120 | 0.77 | NOTUM (0.53) | NOTUMKDM4EALDH1A1MAPK1PDK2 | |
| SCHEMBL15057189 | 0.77 | NOTUM (0.53) | NOTUMKDM4EALDH1A1MAPK1PDK2 | |
| SCHEMBL15720883 | 0.77 | NOTUM (0.53) | NOTUMKDM4EALDH1A1MAPK1PDK2 | |
| SCHEMBL23667424 | 0.77 | CHRM1 (0.47) | NOTUMKDM4EALDH1A1MAPK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |