SCHEMBL8104546

SCHEMBL8104546

COC(=O)c1ccc(OCC2CN(c3ccc(N)cc3)C(=O)O2)cc1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 18/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8113824 0.90 GRM2 (0.70) GRM2
SCHEMBL8114539 0.89 GRM2 (0.64) GRM2
Hydrochloric Acid SCHEMBL8115132 0.88 GRM2 (0.62) GRM2
SCHEMBL8106346 0.87 GRM2 (0.57) GRM2
SCHEMBL8122096 0.86 GRM2 (0.56) GRM2
SCHEMBL8115184 0.82 GRM2 (0.80) GRM2
SCHEMBL24890867 0.82 GRM2 (0.69) GRM2
SCHEMBL8114677 0.82 GRM2 (0.85) GRM2
SCHEMBL8350854 0.82 GRM2 (0.55) GRM2
SCHEMBL7386950 0.81 GRM2 (0.63) GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0605729-B1 OXAZOLIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF TAIHO PHARMACEUTICAL CO LTD (JP) 2000-07-26 EP disclosed
US-5480899-A ANTILIPEMIC AGENTS TAIHO PHARMACEUTICAL CO., LTD. (JP) 1996-01-02 US disclosed
EP-0605729-A1 OXAZOLIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF TAIHO PHARMACEUTICAL CO., LTD. (JP) 1994-07-13 EP disclosed