SCHEMBL8104890

SCHEMBL8104890

O=C1OC(COc2ccc([N+](=O)[O-])cc2)CN1c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 19/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8105930 0.89 GRM2 (0.71) GRM2
SCHEMBL8118884 0.88 GRM2 (0.58) GRM2
SCHEMBL2823305 0.86 GRM2 (1.00) GRM2
SCHEMBL8113587 0.84 GRM2 (0.53) GRM2
SCHEMBL27881024 0.84 GRM2 (0.52) GRM2
SCHEMBL8114677 0.84 GRM2 (0.85) GRM2
SCHEMBL2823430 0.84 GRM2 (0.85) GRM2
SCHEMBL2823046 0.84 GRM2 (0.90) GRM2
SCHEMBL8122096 0.84 GRM2 (0.56) GRM2
SCHEMBL2824383 0.83 GRM2 (0.82) GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0605729-B1 OXAZOLIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF TAIHO PHARMACEUTICAL CO LTD (JP) 2000-07-26 EP disclosed
US-5480899-A ANTILIPEMIC AGENTS TAIHO PHARMACEUTICAL CO., LTD. (JP) 1996-01-02 US disclosed
EP-0605729-A1 OXAZOLIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF TAIHO PHARMACEUTICAL CO., LTD. (JP) 1994-07-13 EP disclosed